Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.34 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.34 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435615 | 0.79 | HDAC6 (0.36) | HDAC6CREBBPKDM1ACHEK1PIP4K2A | |
| SCHEMBL31435635 | 0.75 | PIM1 (0.36) | CREBBPLRRK2CHEK1PIK3CA | |
| SCHEMBL31435585 | 0.73 | HDAC6 (0.37) | HDAC6CREBBPCHEK1PIP4K2APIP4K2B | |
| SCHEMBL31435610 | 0.72 | KDM1A (0.35) | CREBBPLRRK2KDM1ADYRK1ADYRK1B | |
| SCHEMBL31435611 | 0.69 | HDAC6 (0.39) | HDAC6CREBBPKDM1APIP4K2APIP4K2B | |
| SCHEMBL31435599 | 0.68 | PSEN1 (0.49) | CREBBPLRRK2NTRK1 | |
| SCHEMBL31435577 | 0.65 | LRRK2 (0.34) | CREBBPLRRK2NTRK1 | |
| SCHEMBL26773882 | 0.61 | CREBBP (0.38) | CREBBPLRRK2KDM1A | |
| SCHEMBL26773880 | 0.61 | CREBBP (0.38) | CREBBPLRRK2KDM1A | |
| SCHEMBL26773879 | 0.61 | CREBBP (0.38) | CREBBPLRRK2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661516-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2025-03-21 | — | — | CN | disclosed |