Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.34 |
| ▸ | AXL | P30530 | 3/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435588 | 0.75 | HDAC6 (0.37) | PIK3CALRRK2CREBBPCHEK1 | |
| SCHEMBL16320096 | 0.74 | PIK3CA (0.39) | PIM1PIK3CACLK2LRRK2CREBBP | |
| SCHEMBL31435610 | 0.68 | KDM1A (0.35) | PIK3CACLK2LRRK2AXLCREBBP | |
| SCHEMBL31435599 | 0.66 | PSEN1 (0.49) | LRRK2TYRO3AXLCREBBPPSEN1 | |
| SCHEMBL16320341 | 0.66 | PIK3CA (0.40) | PIM1PIK3CALRRK2FYNCHEK1 | |
| SCHEMBL31435577 | 0.65 | LRRK2 (0.34) | LRRK2TYRO3AXLCREBBPPSEN1 | |
| SCHEMBL26765998 | 0.61 | FLT3 (0.38) | PIM1PIK3CALRRK2FYNPIK3CD | |
| SCHEMBL31435585 | 0.61 | HDAC6 (0.37) | PIK3CACREBBPFYNCHEK1PIK3CD | |
| SCHEMBL25408417 | 0.60 | PIK3CD (0.43) | PIM1PIK3CALRRK2AXLFYN | |
| SCHEMBL31435615 | 0.59 | HDAC6 (0.36) | PIK3CACREBBPFYNCHEK1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661516-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2025-03-21 | — | — | CN | disclosed |