Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051114 | 0.73 | CDC7 (0.47) | CDC7NPC1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28738869 | 0.71 | HSD17B1 (0.53) | CSNK2A1CDC7NPC1CYP1A2CYP2D6 | |
| SCHEMBL8352602 | 0.71 | EGFR (0.45) | CDC7NPC1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL19644014 | 0.70 | HSD17B1 (0.56) | PLK1CSNK2A1PLK3CREBBPBRD4 | |
| SCHEMBL31435572 | 0.70 | CREBBP (0.37) | CREBBPAURKATTKAURKBINCENP | |
| SCHEMBL31435620 | 0.69 | PLK1 (0.41) | PLK1CSNK2A1PLK3CREBBPCDC7 | |
| SCHEMBL31435569 | 0.69 | SMN1; SMN2 (0.38) | PLK1CSNK2A1PLK3CREBBPBRD4 | |
| SCHEMBL28738860 | 0.69 | CYP1A2 (0.42) | CSNK2A1CDC7NPC1CYP1A2CYP2D6 | |
| SCHEMBL24177880 | 0.67 | POLB (0.40) | PLK1CSNK2A1PLK3NPC1CYP1A2 | |
| SCHEMBL10426958 | 0.67 | TDP1 (0.53) | PLK1CSNK2A1PLK3NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661516-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2025-03-21 | — | — | CN | disclosed |