Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435598 | 0.79 | PLK1 (0.36) | PLK1CSNK2A1PLK3BMPR1AACVRL1 | |
| SCHEMBL1582995 | 0.75 | HTR7 (0.46) | SMN1; SMN2ALDH1A1BRD4 | |
| SCHEMBL9024407 | 0.72 | HTR2A (0.49) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9445146 | 0.72 | HTR2A (0.50) | SMN1; SMN2ALDH1A1BRD4MAPK1 | |
| SCHEMBL31435593 | 0.69 | PLK1 (0.41) | SMN1; SMN2ALDH1A1PLK1CSNK2A1PLK3 | |
| SCHEMBL31435577 | 0.69 | LRRK2 (0.34) | CREBBPRETJAK3AXL | |
| SCHEMBL9024716 | 0.69 | HTR7 (0.53) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL31435578 | 0.68 | DRD4 (0.44) | ALDH1A1PLK1CSNK2A1PLK3BMPR1A | |
| SCHEMBL15133282 | 0.67 | IGF1R (0.51) | ALDH1A1 | |
| SCHEMBL9024849 | 0.67 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661516-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2025-03-21 | — | — | CN | disclosed |