Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26637666 | 1.00 | SLC6A2 (0.42) | SLC6A2SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL26637709 | 0.87 | SLC6A2 (0.44) | SLC6A2SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL31436641 | 0.87 | SLC6A2 (0.44) | SLC6A2SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL26637568 | 0.84 | SLC6A2 (0.45) | SLC6A2SLC6A3CHRNA1CHRNB1CHRNB2 | |
| SCHEMBL31685947 | 0.84 | SLC6A2 (0.45) | SLC6A2SLC6A3CHRNA1CHRNB1CHRNB2 | |
| SCHEMBL26637876 | 0.81 | OPRM1 (0.42) | SLC6A2SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL26637850 | 0.79 | ALDH1A1 (0.39) | ALDH1A1OPRM1CCR2OPRD1OPRK1 | |
| SCHEMBL31436670 | 0.79 | ALDH1A1 (0.39) | ALDH1A1OPRM1CCR2OPRD1OPRK1 | |
| SCHEMBL7990127 | 0.78 | SLC6A2 (0.41) | SLC6A2SLC6A3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL26637740 | 0.77 | CHRNA1 (0.39) | SLC6A2SLC6A3CHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119486999-A | Azetidine compounds, pharmaceutical compositions thereof, methods of preparation and their use in the treatment of CNS disorders | 伊科诺姆有限公司 | 2025-02-18 | — | — | CN | disclosed |