Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 14/20 | 0.58 |
| ▸ | CHRNB4 | P30926 | 9/20 | 0.58 |
| ▸ | CHRNA3 | P32297 | 9/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.47 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6270030 | 0.89 | CHRNA7 (0.61) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL9183119 | 0.85 | CHRNA7 (0.79) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL24465407 | 0.77 | CHRNA7 (0.65) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL11423649 | 0.77 | CHRNA7 (0.96) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL791296 | 0.76 | MAOB (0.69) | MAOBMAPK1 | |
| SCHEMBL27343171 | 0.75 | CHRNA7 (0.55) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL13385235 | 0.75 | CHRNA7 (1.00) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL10597796 | 0.75 | MAPK1 (0.68) | MAOBALOX15HSD17B10MAPK1TSHR | |
| SCHEMBL8569308 | 0.74 | CHRNA7 (0.54) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL30354177 | 0.74 | CHRNA7 (0.54) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119563628-A | Calcium-containing spray for preventing grape cracking and preparation method thereof | 陕西科技大学 | 2025-03-07 | — | — | CN | claimed |
| CN-119563628-A | Calcium-containing spray for preventing grape cracking and preparation method thereof | 陕西科技大学 | 2025-03-07 | — | — | CN | disclosed |