Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640896 | 0.81 | DRD2 (0.42) | DRD2NAMPTPKMRORCCCR5 | |
| SCHEMBL24572248 | 0.81 | DRD2 (0.42) | DRD2NAMPTPKMRORCCCR5 | |
| SCHEMBL29640893 | 0.81 | DRD2 (0.42) | DRD2NAMPTPKMRORCCCR5 | |
| SCHEMBL31437073 | 0.77 | DRD2 (0.48) | DRD2NAMPTPKMTSHRRORC | |
| SCHEMBL24571646 | 0.77 | DRD2 (0.48) | DRD2NAMPTPKMTSHRRORC | |
| SCHEMBL24571241 | 0.77 | RORC (0.49) | NAMPTPKMTSHRRORCUSP5 | |
| SCHEMBL31437067 | 0.77 | RORC (0.49) | NAMPTPKMTSHRRORCUSP5 | |
| SCHEMBL24571698 | 0.76 | DRD2 (0.47) | DRD2NAMPTPKMTSHRRORC | |
| SCHEMBL29640961 | 0.75 | F13A1 (0.45) | DRD2PKMTSHRRORCCCR5 | |
| SCHEMBL27298520 | 0.75 | F13A1 (0.45) | DRD2PKMTSHRRORCCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |