Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27039415 | 0.90 | CRBN (0.46) | CRBNDDB1DRD3MAPTHTR1A | |
| SCHEMBL27091768 | 0.88 | CRBN (0.50) | CRBNDDB1F10ALDH1A1LMNA | |
| SCHEMBL25170768 | 0.88 | CRBN (0.50) | CRBNDDB1F10ALDH1A1LMNA | |
| SCHEMBL30738820 | 0.88 | CRBN (0.50) | CRBNDDB1F10ALDH1A1LMNA | |
| SCHEMBL27039529 | 0.84 | DDB1 (0.49) | CRBNDDB1DRD2DRD3DRD4 | |
| SCHEMBL30726420 | 0.84 | DDB1 (0.49) | CRBNDDB1DRD2DRD3DRD4 | |
| SCHEMBL31437047 | 0.84 | DDB1 (0.46) | CRBNDDB1 | |
| SCHEMBL30738791 | 0.83 | DDB1 (0.43) | CRBNDDB1F10LMNAHPGD | |
| SCHEMBL24207123 | 0.83 | DDB1 (0.43) | CRBNDDB1F10LMNAHPGD | |
| Hydrochloric Acid SCHEMBL30969032 | 0.83 | DDB1 (0.48) | CRBNDDB1DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |