Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.61 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950977 | 0.88 | CHRM2 (0.61) | CHRM3CHRM2DDB1CRBNDRD2 | |
| Hydrochloric Acid SCHEMBL10944931 | 0.87 | CHRM2 (0.60) | CHRM3CHRM2DRD2DRD4OPRM1 | |
| SCHEMBL2317295 | 0.85 | CHRM4 (0.57) | CHRM3CHRM2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3063295 | 0.81 | CHRM3 (0.59) | CHRM3CHRM2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3655076 | 0.81 | CHRM3 (0.51) | CHRM3CHRM2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22144449 | 0.79 | CHRM3 (0.57) | CHRM3CHRM2DDB1CRBNCYP3A4 | |
| SCHEMBL10955807 | 0.79 | OPRM1 (0.50) | CHRM3CHRM2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11217794 | 0.79 | OPRL1 (0.57) | CHRM3CHRM2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7747502 | 0.79 | CHRM3 (0.53) | CHRM3CHRM2DDB1CRBNCYP3A4 | |
| SCHEMBL9046543 | 0.79 | CHRM4 (0.70) | CHRM3CHRM2OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |