Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749282 | 0.82 | CHRM3 (0.54) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL31437068 | 0.79 | CHRM3 (0.61) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL14450288 | 0.77 | OPRL1 (0.64) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL3958334 | 0.74 | OPRL1 (0.51) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL18845203 | 0.73 | ACHE (0.57) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL7747497 | 0.72 | DDB1 (0.56) | DRD2DRD4DRD3DDB1CRBN | |
| SCHEMBL3075361 | 0.72 | OPRL1 (0.66) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL3063295 | 0.71 | CHRM3 (0.59) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL4257757 | 0.71 | ACHE (0.69) | DRD2DRD4DRD3ACHE | |
| SCHEMBL2395111 | 0.71 | RECQL (0.62) | DRD2DRD4DRD3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027087-A2 | PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |