Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22505342 | 1.00 | GPR119 (0.46) | GPR119ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL30798343 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTMAPTKDM4EKMT2A | |
| SCHEMBL24717493 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTMAPTKDM4EKMT2A | |
| SCHEMBL20521289 | 0.84 | ALDH1A1 (0.47) | GPR119ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL710593 | 0.84 | GPR119 (0.53) | GPR119ALDH1A1HTTMAPTNR1H2 | |
| SCHEMBL22505523 | 0.83 | ALDH1A1 (0.47) | GPR119ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL31437107 | 0.83 | ALDH1A1 (0.47) | GPR119ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL23703371 | 0.83 | ALDH1A1 (0.47) | GPR119ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL25691277 | 0.83 | TSHR (0.49) | ALDH1A1HTTMAPTKDM4EKMT2A | |
| SCHEMBL22505542 | 0.81 | ALDH1A1 (0.46) | GPR119ALDH1A1HTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152967-A | Bifunctional compounds containing 2, 5-substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |