Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | PDE8B | O95263 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15575388 | 0.97 | OPRD1 (0.50) | KDM1APRMT5OPRD1PDE8BMEN1 | |
| SCHEMBL4471009 | 0.84 | MEN1 (0.46) | KDM1APDE8BMEN1KMT2AHDAC1 | |
| SCHEMBL2200178 | 0.83 | OPRD1 (0.50) | KDM1APRMT5OPRD1MEN1KMT2A | |
| SCHEMBL16333400 | 0.82 | KDM1A (0.49) | KDM1APRMT5OPRD1PDE8BMEN1 | |
| SCHEMBL19540688 | 0.82 | APP (0.49) | KDM1AOPRD1HDAC1FPR3FPR2 | |
| SCHEMBL1462901 | 0.82 | FPR3 (0.50) | KDM1APRMT5OPRD1MEN1KMT2A | |
| SCHEMBL29825424 | 0.81 | NPC1 (0.43) | KDM1APRMT5OPRD1MEN1KMT2A | |
| SCHEMBL19141219 | 0.81 | PRMT5 (0.53) | KDM1APRMT5OPRD1PDE8BTRPV1 | |
| SCHEMBL5337684 | 0.81 | PRMT5 (0.53) | KDM1APRMT5OPRD1PDE8BTRPV1 | |
| SCHEMBL13889153 | 0.81 | PTGER4 (0.42) | KDM1APRMT5OPRD1PDE8BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |