Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31437474

CC1(OCc2ccccc2)CNC1.O=C(O)C(F)(F)F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CES1 P23141 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HTR2C P28335 1/20 0.38
BACE1 P56817 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20212763 0.74 CHRM1 (0.42)
Trifluoroacetic Acid SCHEMBL27563331 0.73 ALDH1A1 (0.50) HDAC3HDAC1HDAC2NCOR2KMT2A
Trifluoroacetic Acid SCHEMBL27694734 0.72 F2 (0.40) HDAC3HDAC1HDAC2NCOR2ALDH1A1
Trifluoroacetic Acid SCHEMBL27579421 0.72 TSHR (0.62) ALDH1A1CES1
SCHEMBL19567884 0.72 TSHR (0.38) HTR2C
Trifluoroacetic Acid SCHEMBL31727658 0.72 AGTR2 (0.38) CES1SLC6A2SLC6A3
Trifluoroacetic Acid SCHEMBL15019736 0.71 HTR2C (0.44) HDAC1KMT2AMEN1HTR2C
SCHEMBL7076809 0.70 TSHR (0.46) KMT2AALDH1A1SLC6A2SLC6A3TDP1
Trifluoroacetic Acid SCHEMBL30312795 0.70 ALDH1A1 (0.43) KMT2AMEN1ALDH1A1HTR2C
SCHEMBL17848454 0.70 TACR1 (0.51) KMT2AMEN1ALDH1A1SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025037940-A1 PYRAZOLE-1-CARBOXAMIDES AS RIP1 KINASE INHIBITORS BISICHEM CO., LTD. (KR) 2025-02-20 WO disclosed