SCHEMBL31437795

SCHEMBL31437795

CC(C)=Cc1cc(Br)nn1C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 10/20 0.43
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
EZH2 Q15910 1/20 0.40
FPR2 P25090 1/20 0.40
PTPN2 P17706 1/20 0.40
PTPN1 P18031 1/20 0.40
PTPN6 P29350 1/20 0.40
NR3C1 P04150 2/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31437751 0.87 FPR2 (0.43) MAPTFPR2HPGD
SCHEMBL23546415 0.84 GPR119 (0.46) GPR119KDM4EMAPTTHRBFPR2
SCHEMBL23546379 0.83 GPR119 (0.48) GPR119KDM4EMAPTTHRBEZH2
SCHEMBL31437929 0.83 CHRM2 (0.50) GPR119
SCHEMBL31466409 0.82 GPR119 (0.43) GPR119KDM4EMAPTTHRBEZH2
SCHEMBL31466122 0.81 MAPT (0.46) GPR119KDM4EMAPTTHRBEZH2
SCHEMBL31437967 0.78 MAPT (0.43) GPR119KDM4EMAPTTHRBEZH2
SCHEMBL25294568 0.78 PIK3CD (0.42) GPR119KDM4EMAPTTHRB
SCHEMBL31437782 0.75 KDM4E (0.35) KDM4EHPGD
SCHEMBL31437970 0.75 KDM4E (0.35) KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025011533-A1 CARBOXYLIC ACID COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海宇道生物技术有限公司 2025-01-16 WO disclosed