SCHEMBL31437865

SCHEMBL31437865

COCCOc1ccc(B(O)O)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.59
KDR P35968 4/20 0.44
S1PR4 O95977 3/20 0.43
L3MBTL1 Q9Y468 4/20 0.43
MAPT P10636 4/20 0.43
HPGD P15428 4/20 0.43
RAB9A P51151 3/20 0.43
POLB P06746 2/20 0.43
NPC1 O15118 2/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX12 P18054 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TTR P02766 1/20 0.42
KDM4E B2RXH2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2561475 0.87 L3MBTL1 (0.46) ENPP2KDRL3MBTL1MAPTHPGD
SCHEMBL182934 0.85 ENPP2 (0.57) ENPP2L3MBTL1MAPTHPGDRAB9A
SCHEMBL28686847 0.85 ENPP2 (0.61) ENPP2S1PR4L3MBTL1MAPTHPGD
SCHEMBL29408089 0.85 ENPP2 (0.61) ENPP2S1PR4L3MBTL1MAPTHPGD
SCHEMBL1516637 0.85 KDR (0.50) ENPP2KDRL3MBTL1MAPTHPGD
SCHEMBL257737 0.84 ENPP2 (0.56) ENPP2L3MBTL1MAPTHPGDRAB9A
SCHEMBL430117 0.82 KDR (0.51) ENPP2KDRL3MBTL1MAPTHPGD
SCHEMBL2561666 0.82 KDR (0.45) ENPP2KDRL3MBTL1HPGDRAB9A
SCHEMBL2316275 0.81 ENPP2 (0.60) ENPP2L3MBTL1MAPTHPGDRAB9A
SCHEMBL1823994 0.81 KDR (0.44) ENPP2KDRL3MBTL1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025011533-A1 CARBOXYLIC ACID COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海宇道生物技术有限公司 2025-01-16 WO disclosed