SCHEMBL3143807

SCHEMBL3143807

O=C(OC1=CCC1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.53
MAPT P10636 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
F2 P00734 1/20 0.50
LMNA P02545 1/20 0.50
TSHR P16473 2/20 0.47
TDP1 Q9NUW8 3/20 0.46
MEN1 O00255 3/20 0.46
PARP10 Q53GL7 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 1/20 0.43
PKM P14618 1/20 0.43
SLC6A3 Q01959 1/20 0.43
GRM5 P41594 1/20 0.43
MAPK1 P28482 1/20 0.43
TOP1 P11387 1/20 0.42
TP53 P04637 1/20 0.42
JAK2 O60674 1/20 0.42
USP2 O75604 1/20 0.42
ESR1 P03372 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9341204 0.87 KMT2A (0.49) KMT2AMAPTSMN1; SMN2F2LMNA
SCHEMBL6353529 0.85 KMT2A (0.51) KMT2AMAPTSMN1; SMN2F2LMNA
SCHEMBL13226211 0.79 KMT2A (0.45) KMT2AMAPTSMN1; SMN2F2LMNA
SCHEMBL31197024 0.76 KMT2A (0.53) KMT2AMAPTSMN1; SMN2F2LMNA
SCHEMBL30755222 0.76 KMT2A (0.41) KMT2AMAPTSMN1; SMN2F2LMNA
SCHEMBL8138563 0.74 KMT2A (0.39) KMT2AMAPTSMN1; SMN2LMNAMEN1
SCHEMBL2788454 0.74 KMT2A (0.47) KMT2AMAPTSMN1; SMN2F2LMNA
SCHEMBL6942981 0.74 MAPT (0.60) KMT2AMAPTSMN1; SMN2F2LMNA
SCHEMBL5551848 0.73 LMNA (0.64) KMT2AMAPTSMN1; SMN2F2LMNA
SCHEMBL8132876 0.73 MAPK1 (0.41) KMT2AMAPTSMN1; SMN2LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8912264-B2 Aqueous ethylene/vinyl alcohol copolymer dispersion SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2014-12-16 US disclosed
EP-1816159-B1 AQUEOUS ETHYLENE/VINYL ALCOHOL COPOLYMER DISPERSION SUMITOMO SEIKA CHEMICALS (JP) 2010-02-24 EP disclosed
US-20090149593-A1 AQUEOUS ETHYLENE/VINYL ALCOHOL COPOLYMER DISPERSION SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2009-06-11 US disclosed
EP-1816159-A1 AQUEOUS ETHYLENE/VINYL ALCOHOL COPOLYMER DISPERSION SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2007-08-08 EP disclosed