Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31438304 | 0.82 | CYP3A4 (0.32) | — | |
| SCHEMBL30752365 | 0.80 | CLK1 (0.38) | — | |
| SCHEMBL30752376 | 0.79 | — | — | |
| SCHEMBL31438267 | 0.77 | MET (0.33) | — | |
| SCHEMBL31438273 | 0.77 | AXL (0.36) | PRMT5WDR77 | |
| SCHEMBL31438262 | 0.76 | — | — | |
| SCHEMBL31438261 | 0.76 | NPY5R (0.34) | — | |
| SCHEMBL31319636 | 0.76 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL31438249 | 0.75 | — | — | |
| SCHEMBL31319667 | 0.75 | RXFP1 (0.36) | PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585257-A | Novel 7-substituted indole sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-03-07 | — | — | CN | disclosed |