Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31438256 | 0.86 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL31438269 | 0.86 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL31319667 | 0.85 | RXFP1 (0.36) | PRMT5 | |
| SCHEMBL31438293 | 0.81 | HTR2C (0.34) | PRMT5WDR77 | |
| SCHEMBL31438292 | 0.80 | CCR1 (0.37) | CCR9 | |
| SCHEMBL31438257 | 0.80 | CCR9 (0.30) | CCR9 | |
| SCHEMBL31438267 | 0.79 | MET (0.33) | — | |
| SCHEMBL31438281 | 0.79 | DCLK1 (0.33) | CCR9 | |
| SCHEMBL31438261 | 0.78 | NPY5R (0.34) | CCR9 | |
| SCHEMBL31438244 | 0.76 | SCN9A (0.31) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585257-A | Novel 7-substituted indole sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |