SCHEMBL31438436

SCHEMBL31438436

CCC(CC(=O)ON1C(=O)CCC1=O)N1C(=O)C=CC1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
BLM P54132 1/20 0.34
WRN Q14191 1/20 0.34
HIF1A Q16665 1/20 0.34
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
LMNA P02545 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5316357 0.89 KMT2A (0.33) KMT2AATMALDH1A1CYP1A2HPGD
SCHEMBL1353975 0.86 ALDH1A1 (0.33) KMT2AATMALDH1A1CYP1A2HPGD
SCHEMBL29078555 0.84 KMT2A (0.32) KMT2AATMALDH1A1CYP1A2HPGD
SCHEMBL10428722 0.84 KMT2A (0.33) KMT2AALDH1A1CYP1A2HPGDCYP2C19
SCHEMBL17865899 0.83 KMT2A (0.35) KMT2AALDH1A1CYP1A2HPGDCYP2C19
SCHEMBL1726687 0.82 KMT2A (0.36) KMT2AATMALDH1A1CYP1A2HPGD
SCHEMBL28954380 0.82 KMT2A (0.35) KMT2AATMALDH1A1CYP1A2HPGD
SCHEMBL28497468 0.81 KMT2A (0.34) KMT2AATMALDH1A1CYP1A2HPGD
SCHEMBL3735742 0.77 ALDH1A1 (0.36) KMT2AATMALDH1A1CYP1A2HPGD
SCHEMBL28862668 0.76 KMT2A (0.32) KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025027389-A1 BIOLOGICALLY ACTIVE COMPOUNDS COMPRISING A STAPLED OR STITCHED PEPTIDE SUTURA THERAPEUTICS LIMITED (GB) 2025-02-06 WO disclosed