Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | WRN | Q14191 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428722 | 0.96 | KMT2A (0.33) | KMT2ASMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL1353975 | 0.91 | ALDH1A1 (0.33) | KMT2AALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL28363104 | 0.84 | SMN1; SMN2 (0.36) | KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31438436 | 0.83 | KMT2A (0.35) | KMT2AALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL28088476 | 0.80 | KMT2A (0.31) | KMT2ASMN1; SMN2 | |
| SCHEMBL18122756 | 0.79 | SMN1; SMN2 (0.38) | KMT2ASMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL5062198 | 0.79 | KMT2A (0.31) | KMT2ASMN1; SMN2 | |
| SCHEMBL5316357 | 0.78 | KMT2A (0.33) | KMT2AALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL17865898 | 0.78 | ALOX12 (0.43) | SMN1; SMN2HPGD | |
| SCHEMBL12261668 | 0.78 | SMN1; SMN2 (0.40) | KMT2ASMN1; SMN2ALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776389-B1 | SIALIC ACID DERIVATIVES | LIPOXEN TECHNOLOGIES LTD (GB) | 2016-06-29 | — | — | EP | claimed |