Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31438540 | 0.90 | MAPK8 (0.35) | MAPK8KDM4ELMNAADORA3ADORA2A | |
| SCHEMBL18153003 | 0.87 | MAPK8 (0.42) | MAPK8KDM4ELMNAADORA3ADORA2A | |
| SCHEMBL31438557 | 0.76 | MAPK8 (0.42) | MAPK8KDM4ELMNAADORA3ADORA2A | |
| SCHEMBL18153007 | 0.72 | PTK2 (0.44) | MAPK8KDM4ELMNAADORA3CYP1A2 | |
| SCHEMBL25188090 | 0.72 | APP (0.37) | PTPN1MAPT | |
| SCHEMBL31438509 | 0.72 | APP (0.37) | PTPN1MAPT | |
| SCHEMBL25189945 | 0.70 | KDM4E (0.42) | MAPK8KDM4ELMNAADORA3ADORA2A | |
| SCHEMBL24427232 | 0.69 | AKT1 (0.36) | MAPK14 | |
| SCHEMBL9297719 | 0.69 | KDM4E (0.66) | MAPK8KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL27398573 | 0.67 | ADORA3 (0.46) | MAPK8KDM4ELMNAADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134035-B | 3- (1H-imidazol-2-yl) -2,3,8 a-tetrahydroindol-5 (1H) -one derivatives useful as factor XIA inhibitors | 詹森药业有限公司 | 2025-03-11 | — | — | CN | disclosed |