Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17479507 | 1.00 | TSHR (0.46) | TSHRTDP1TP53HTTNPSR1 | |
| SCHEMBL31438508 | 0.83 | TSHR (0.43) | TSHRTDP1TP53HTTNPSR1 | |
| SCHEMBL19138136 | 0.82 | TSHR (0.45) | TSHRTDP1TP53HTTNPSR1 | |
| SCHEMBL1401560 | 0.82 | TSHR (0.57) | TSHRHTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL7467330 | 0.80 | TSHR (0.70) | TSHRTDP1TP53HTTNPSR1 | |
| SCHEMBL29183380 | 0.78 | TSHR (0.44) | TSHRTDP1NPSR1ALDH1A1KDM4E | |
| SCHEMBL30251605 | 0.78 | CA12 (0.44) | TSHRTDP1TP53HTTNPSR1 | |
| SCHEMBL10281224 | 0.76 | SMN1; SMN2 (0.40) | TSHRTDP1TP53HTTNPSR1 | |
| SCHEMBL24529118 | 0.76 | MRGPRX4 (0.51) | TSHRHTTALDH1A1KDM4ELMNA | |
| SCHEMBL30280757 | 0.76 | MRGPRX4 (0.51) | TSHRHTTALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134035-B | 3- (1H-imidazol-2-yl) -2,3,8 a-tetrahydroindol-5 (1H) -one derivatives useful as factor XIA inhibitors | 詹森药业有限公司 | 2025-03-11 | — | — | CN | disclosed |