Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 8/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 8/20 | 0.42 |
| ▸ | GSK3B | P49841 | 5/20 | 0.42 |
| ▸ | FLT3 | P36888 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30618993 | 0.78 | HTR1A (0.52) | EPHX2HRH4HTR2AHTR2CSLC6A4 | |
| Trifluoroacetic Acid SCHEMBL28705254 | 0.76 | AOC3 (0.44) | HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL18453319 | 0.76 | AOC3 (0.44) | HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL29544383 | 0.76 | AOC3 (0.44) | HRH4HRH3 | |
| SCHEMBL25411523 | 0.73 | HTR2A (0.54) | EPHX2HTR2AHTR2CSLC6A4PRKCA | |
| SCHEMBL30263296 | 0.73 | HTR2A (0.54) | EPHX2HTR2AHTR2CSLC6A4PRKCA | |
| 2-Piperazin-1-Yl-Pyrimidine SCHEMBL26600776 | 0.73 | KDM4E (0.66) | EPHX2HRH4HRH3RAD52UBE2N | |
| Trifluoroacetic Acid SCHEMBL18453329 | 0.73 | CHRNB2 (0.47) | HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL30782681 | 0.72 | HTR2A (0.52) | EPHX2HTR2AHTR2CSLC6A4PRKCA | |
| SCHEMBL30124461 | 0.72 | HTR2A (0.55) | EPHX2HTR2AHTR2CSLC6A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059178-A1 | N-(PYRIDIN-2-YL)-4-(THIAZOL-5-YL)PYRIMIDIN-2-AMINE DERIVATIVES AS THERAPEUTIC COMPOUNDS | Aucentra Thereapeutics Pty LTD (AU) | 2025-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059178-A1 | N-(PYRIDIN-2-YL)-4-(THIAZOL-5-YL)PYRIMIDIN-2-AMINE DERIVATIVES AS THERAPEUTIC COMPOUNDS | CDK4, CDK6, CDK2 | EPHX2 3941/4885HRH4 2686/4885BACE1 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.