SCHEMBL31439366

SCHEMBL31439366

N#Cc1ccc(Nc2c([N+](=O)[O-])cnc3ccc(Br)cc23)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 1/20 0.38
SRC P12931 2/20 0.37
EGFR P00533 2/20 0.37
ERBB2 P04626 1/20 0.37
TNF P01375 2/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 2/20 0.36
HTT P42858 2/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
NOD2 Q9HC29 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NOD1 Q9Y239 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31439302 0.82 EGFR (0.39) SRCEGFRERBB2TNFALDH1A1
SCHEMBL994789 0.78 TNF (0.45) SRCEGFRTNFMAPTALDH1A1
SCHEMBL14872855 0.78 MAPK1 (0.43) EGFRTNFMAPTALDH1A1MAPK1
SCHEMBL27915461 0.78 MEN1 (0.43) EGFRTNFMAPTALDH1A1MAPK1
SCHEMBL30849442 0.76 ALDH1A1 (0.44) EGFRTNFMAPTALDH1A1MAPK1
SCHEMBL27896846 0.76 ALDH1A1 (0.44) EGFRTNFMAPTALDH1A1MAPK1
SCHEMBL14872843 0.76 PDE4B (0.48) EGFRERBB2TNFMAPTALDH1A1
SCHEMBL168459 0.75 EGFR (0.49) SRCEGFRERBB2
SCHEMBL28598956 0.74 EGFR (0.37) EGFRERBB2MEN1KMT2A
SCHEMBL28084108 0.74 LMNA (0.41) EGFRTNFMAPTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661531-A Imidazolone compound as well as preparation method and application thereof 北京富龙康泰生物技术有限公司 2025-03-21 CN disclosed