SCHEMBL31440712

SCHEMBL31440712

CC(C)(C)OC(=O)C[C@H](N)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GNPAT O15228 1/20 0.52
▸ OPRK1 P41145 1/20 0.47
▸ ERAP2 Q6P179 1/20 0.47
▸ LNPEP Q9UIQ6 1/20 0.47
▸ ECE1 P42892 1/20 0.46
▸ CPB2 Q96IY4 1/20 0.45
▸ CTSS P25774 2/20 0.44
▸ CTSL P07711 1/20 0.44
▸ CTSB P07858 1/20 0.44
▸ CTSK P43235 1/20 0.44
▸ MMP2 P08253 1/20 0.44
▸ REN P00797 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30852859 0.87 ABCB1 (0.43) GNPATOPRK1ERAP2LNPEPCPB2
SCHEMBL3789929 0.87 CTSS (0.59) GNPATECE1CTSSCTSLCTSB
SCHEMBL29839818 0.87 CTSS (0.59) GNPATECE1CTSSCTSLCTSB
SCHEMBL3789933 0.87 CTSS (0.59) GNPATECE1CTSSCTSLCTSB
SCHEMBL31170895 0.85 GNPAT (0.57) GNPATOPRK1ERAP2LNPEPECE1
SCHEMBL29573446 0.85 GNPAT (0.57) GNPATOPRK1ERAP2LNPEPECE1
SCHEMBL31214774 0.85 GNPAT (0.60) GNPATERAP2LNPEPECE1CPB2
SCHEMBL31214786 0.85 GNPAT (0.60) GNPATERAP2LNPEPECE1CPB2
SCHEMBL1711769 0.84 GNPAT (0.63) GNPATOPRK1ERAP2LNPEPECE1
SCHEMBL1711598 0.84 GNPAT (0.63) GNPATOPRK1ERAP2LNPEPECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025051994-A1 IONIZABLE LIPID NANOPARTICLES COAVE THERAPEUTICS (FR) 2025-03-13 — — WO disclosed
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