Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10182367 | 0.89 | PRSS1 (0.46) | PRSS1HDAC6ALDH1A1KDM4EGAA | |
| SCHEMBL31638008 | 0.86 | PRSS1 (0.38) | PRSS1CYP19A1ALDH1A1KDM4EGAA | |
| SCHEMBL6248663 | 0.79 | HDAC6 (0.63) | PRSS1CYP19A1HDAC6ALDH1A1KDM4E | |
| SCHEMBL30516524 | 0.79 | PRSS1 (0.49) | PRSS1CYP19A1HDAC6ALDH1A1HSD17B10 | |
| SCHEMBL30516497 | 0.79 | HDAC6 (0.63) | PRSS1CYP19A1HDAC6ALDH1A1KDM4E | |
| SCHEMBL2794943 | 0.79 | PRSS1 (0.49) | PRSS1CYP19A1HDAC6ALDH1A1HSD17B10 | |
| SCHEMBL1464213 | 0.79 | PRSS1 (0.49) | PRSS1CYP19A1HDAC6ALDH1A1KDM4E | |
| SCHEMBL8334585 | 0.79 | PRSS1 (0.49) | PRSS1CYP19A1HDAC6ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL4862759 | 0.78 | HDAC6 (0.61) | PRSS1CYP19A1HDAC6ALDH1A1KDM4E | |
| SCHEMBL18630747 | 0.76 | PTGER4 (0.51) | PRSS1HDAC6ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025053850-A1 | COVALENT KRAS-BINDING COMPOUNDS FOR MEDICAL TREATMENT | HYKU BIOSCIENCES INC. (US) | 2025-03-13 | — | — | WO | disclosed |