Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ATF1 | P18846 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418903 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL22208142 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL30664848 | 0.88 | ATR (0.38) | ATRALDH1A1KDM4ENPC1MAPK1 | |
| SCHEMBL26656273 | 0.88 | ATR (0.38) | ATRALDH1A1KDM4ENPC1MAPK1 | |
| SCHEMBL31497664 | 0.86 | KEAP1 (0.32) | ALDH1A1KDM4EGAA | |
| SCHEMBL23043008 | 0.78 | NPC1 (0.37) | ALDH1A1KDM4ENPC1MAPK1PDK1 | |
| SCHEMBL29921963 | 0.78 | NPC1 (0.37) | ALDH1A1KDM4ENPC1MAPK1PDK1 | |
| SCHEMBL29680555 | 0.78 | ATR (0.62) | ATRMAPTPDK1PDK2PDK3 | |
| SCHEMBL23043021 | 0.78 | ATR (0.62) | ATRMAPTPDK1PDK2PDK3 | |
| SCHEMBL31534296 | 0.78 | TSHR (0.31) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025053850-A1 | COVALENT KRAS-BINDING COMPOUNDS FOR MEDICAL TREATMENT | HYKU BIOSCIENCES INC. (US) | 2025-03-13 | — | — | WO | disclosed |