SCHEMBL3144258

SCHEMBL3144258

C[CH]C(CC)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
MIF P14174 1/20 0.39
TRPA1 O75762 3/20 0.38
HKDC1 Q2TB90 1/20 0.38
TAAR1 Q96RJ0 4/20 0.38
HTR2A P28223 3/20 0.38
HRH1 P35367 2/20 0.38
AOC3 Q16853 1/20 0.37
NOS3 P29474 1/20 0.37
NOS2 P35228 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
POLB P06746 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28607657 1.00 LMNA (0.48) LMNAMIFTRPA1HKDC1TAAR1
SCHEMBL5855883 0.82 LMNA (0.45) LMNAMIFTRPA1HKDC1TAAR1
SCHEMBL5855884 0.82 LMNA (0.45) LMNAMIFTRPA1HKDC1TAAR1
SCHEMBL233437 0.82 AOC3 (0.43) LMNATRPA1TAAR1HTR2AHRH1
SCHEMBL9921450 0.79 LMNA (0.46) LMNAMIFTRPA1HKDC1TAAR1
SCHEMBL10012533 0.79 LMNA (0.46) LMNAMIFTRPA1HKDC1TAAR1
SCHEMBL3534814 0.79 LMNA (0.46) LMNAMIFTRPA1HKDC1TAAR1
SCHEMBL13452609 0.79 LMNA (0.46) LMNAMIFTRPA1HKDC1TAAR1
SCHEMBL218804 0.79 LMNA (0.46) LMNAMIFTRPA1HKDC1TAAR1
SCHEMBL3276260 0.79 LMNA (0.46) LMNAMIFTRPA1HKDC1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191533-B1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF SIRRUS INC (US) 2020-11-04 EP claimed
EP-1819776-B1 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PROD INC (US) 2010-03-03 EP claimed
US-7276553-B2 Aesthetic, stable chromatic emulsions AVON PRODUCTS, INC. (US) 2007-10-02 US claimed
US-20060128883-A1 Aesthetic, stable chromatic emulsions AVON PRODUCTS, INC. 2006-06-15 US claimed
EP-0411332-B1 Antiviral peptides having a 2-oxoalkyl amino acid side chain BIO MEGA BOEHRINGER INGELHEIM (CA) 1995-12-06 EP claimed
EP-0411332-A1 Antiviral peptides having a 2-oxoalkyl amino acid side chain BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1991-02-06 EP claimed
CN-112969775-A Cleaning composition 诺维信公司 2021-06-15 CN disclosed
CN-112899086-A Detergent composition 诺维信公司 2021-06-04 CN disclosed
CN-108350400-B Laundry washing method, use of polypeptides and detergent compositions 诺维信公司 2021-03-30 CN disclosed
CN-106164236-B Detergent composition 诺维信公司 2021-02-02 CN disclosed
CN-106164237-B Detergent composition 诺维信公司 2021-01-05 CN disclosed
EP-1819776-B1 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PROD INC (US) 2010-03-03 EP disclosed
US-7276553-B2 Aesthetic, stable chromatic emulsions AVON PRODUCTS, INC. (US) 2007-10-02 US disclosed
EP-0411332-B1 Antiviral peptides having a 2-oxoalkyl amino acid side chain BIO MEGA BOEHRINGER INGELHEIM (CA) 1995-12-06 EP disclosed
EP-0414200-B1 Salts of optically active 4-hydroxy-8-(3-lower alkoxy-4-phenylsulfinylphenyl)pyrazolo [1,5-a]-1,3,5-triazines and a process for production thereof OTSUKA PHARMA CO LTD (JP) 1995-08-02 EP disclosed
CN-1028528-C Salts of optically active 4-hydroxy-8-(3-lower alkoxy-4-phenylsulfinylphenyl) pyrazolo [1,5-a]-1,3,5-triazines OTSUKA PHARMA CO LTD (JP) 1995-05-24 CN disclosed
US-5137887-A Xanthine oxidase inhibitors, antipodagric agents OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1992-08-11 US disclosed
CN-1049664-A Optically active 4-hydroxyl-8-(3-low-alkoxy-4-phenyl sulfinyl phenyl) pyrazolo [1,5-α]-1,3,5-triazines salt and method for making thereof OTSUKA PHARMA CO LTD (JP) 1991-03-06 CN disclosed
EP-0414200-A2 Salts of optically active 4-hydroxy-8-(3-lower alkoxy-4-phenylsulfinylphenyl)pyrazolo [1,5-a]-1,3,5-triazines and a process for production thereof OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1991-02-27 EP disclosed
EP-0411332-A1 Antiviral peptides having a 2-oxoalkyl amino acid side chain BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1991-02-06 EP disclosed