SCHEMBL5855883

SCHEMBL5855883

C/C=C/C(CC)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
MIF P14174 1/20 0.37
TRPA1 O75762 3/20 0.36
HKDC1 Q2TB90 1/20 0.36
TAAR1 Q96RJ0 3/20 0.35
HTR2A P28223 2/20 0.35
HRH1 P35367 1/20 0.35
AOC3 Q16853 1/20 0.35
NOS3 P29474 1/20 0.35
NOS2 P35228 1/20 0.35
PKM P14618 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5855884 1.00 LMNA (0.45) LMNAMEN1KMT2AATMMIF
SCHEMBL5853862 0.83 AOC3 (0.41) LMNAMEN1KMT2AATMTRPA1
SCHEMBL5853865 0.83 AOC3 (0.41) LMNAMEN1KMT2AATMTRPA1
SCHEMBL28607657 0.82 LMNA (0.48) LMNAMEN1KMT2AMIFTRPA1
SCHEMBL3144258 0.82 LMNA (0.48) LMNAMEN1KMT2AMIFTRPA1
SCHEMBL9747820 0.81 LMNA (0.43) LMNAMEN1KMT2AMIFTRPA1
SCHEMBL9747815 0.81 LMNA (0.43) LMNAMEN1KMT2AMIFTRPA1
SCHEMBL5855505 0.80 POLB (0.41) LMNAHTR2AHRH1AOC3POLB
SCHEMBL5855509 0.80 POLB (0.41) LMNAHTR2AHRH1AOC3POLB
SCHEMBL4615601 0.79 MEN1 (0.47) LMNAMEN1KMT2AHTR2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed
US-4258171-A Polyphosphazene polymers containing substituted alkyl/cycloalkyl substituents THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-03-24 US disclosed