Sulfuric Acid

Sulfuric Acid

SCHEMBL31442998

Cc1nc2cccc(C)c2c(C)c1C.O=S(=O)(O)O

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 13/20 0.44
PARP1 P09874 2/20 0.44
PDE10A Q9Y233 1/20 0.40
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CTRB1 P17538 1/20 0.37
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29791541 0.89 ELANE (0.47) ELANEPARP1CTRB1ACHE
SCHEMBL3885065 0.89 ELANE (0.47) ELANEPARP1CTRB1ACHE
SCHEMBL10552382 0.82 ELANE (0.46) ELANEPARP1CTRB1ACHE
SCHEMBL10552388 0.79 ELANE (0.44) ELANEPARP1CTRB1ACHE
SCHEMBL10258857 0.75 PDE10A (0.54) ELANEPARP1PDE10AKDM4EGAA
SCHEMBL480946 0.74 ELANE (0.44) ELANEPARP1KDM4ELMNAGAA
SCHEMBL480945 0.74 GAA (0.46) PDE10AKDM4ELMNAGAAMAPT
SCHEMBL25190852 0.73 EPHB4 (0.44) ELANEPARP1PDE10AKDM4EHTT
SCHEMBL17506412 0.73 ELANE (0.43) ELANEPARP1ACHE
SCHEMBL28386669 0.71 ELANE (0.42) ELANEPARP1KMT2ACTRB1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113631549-B Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2025-01-17 CN disclosed