Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP9 | P55211 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | PYGM | P11217 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443810 | 1.00 | PDE5A (0.33) | PDE5AFFAR2CASP1CASP4CASP5 | |
| SCHEMBL31443571 | 0.91 | PDE5A (0.33) | PDE5AFFAR2CASP1CASP4CASP5 | |
| SCHEMBL31443494 | 0.91 | PDE5A (0.33) | PDE5AFFAR2CASP1CASP4CASP5 | |
| SCHEMBL31443600 | 0.86 | CCR1 (0.37) | PDE5AFFAR2CASP1CASP4CASP5 | |
| SCHEMBL31443683 | 0.86 | CCR1 (0.37) | PDE5AFFAR2CASP1CASP4CASP5 | |
| SCHEMBL31443633 | 0.84 | CASP1 (0.39) | PDE5AFFAR2CASP1CASP4CASP5 | |
| SCHEMBL31443624 | 0.84 | CASP1 (0.39) | PDE5AFFAR2CASP1CASP4CASP5 | |
| SCHEMBL31443490 | 0.83 | CASP1 (0.37) | PDE5AFFAR2CASP1CASP4CASP5 | |
| SCHEMBL31443576 | 0.83 | CASP1 (0.37) | PDE5AFFAR2CASP1CASP4CASP5 | |
| SCHEMBL31443453 | 0.82 | CASP1 (0.37) | PDE5AFFAR2CASP1CASP4CASP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | claimed |
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |