SCHEMBL31444009

SCHEMBL31444009

O=C1CCC(CNc2cccc(SCc3ccccc3)c2)C(=O)N1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.54
DDB1 Q16531 8/20 0.50
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4398954 0.81 CRBN (0.60) CRBNDDB1
SCHEMBL31443747 0.78 CRBN (0.50) CRBNDDB1MAOAMAOB
SCHEMBL31443704 0.77 CRBN (0.49) CRBNDDB1
SCHEMBL31443938 0.77 CRBN (0.48) CRBNDDB1
SCHEMBL4390838 0.76 GAA (0.47) CRBNDDB1
SCHEMBL4399737 0.74 CRBN (0.55) CRBNDDB1
SCHEMBL4400484 0.74 KIF11 (0.48) CRBNDDB1
SCHEMBL4390852 0.74 CRBN (0.55) CRBNDDB1
SCHEMBL31444129 0.73 CRBN (0.62) CRBNDDB1MAOAMAOB
SCHEMBL31443822 0.73 CRBN (0.53) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed