SCHEMBL31444046

SCHEMBL31444046

O=C1CCN(c2ccc(C3CCNCC3)c(OS(=O)(=O)F)c2)C(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 6/20 0.43
▸ DDB1 Q16531 5/20 0.43
▸ HTR6 P50406 11/20 0.36
▸ SLC6A2 P23975 3/20 0.34
▸ SLC6A4 P31645 3/20 0.34
▸ SLC6A3 Q01959 3/20 0.34
▸ HTR1A P08908 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444240 1.00 CRBN (0.43) CRBNDDB1HTR6SLC6A2SLC6A4
SCHEMBL31444089 0.89 DDB1 (0.43) CRBNDDB1HTR6
SCHEMBL31443918 0.84 CRBN (0.45) CRBNDDB1HTR6
SCHEMBL31444132 0.83 DDB1 (0.38) CRBNDDB1
SCHEMBL31444055 0.81 DDB1 (0.44) CRBNDDB1
SCHEMBL25176099 0.81 CRBN (0.49) CRBNDDB1HTR6SLC6A2SLC6A4
SCHEMBL30376327 0.81 CRBN (0.49) CRBNDDB1HTR6SLC6A2SLC6A4
SCHEMBL31444107 0.81 DDB1 (0.45) CRBNDDB1HTR6SLC6A2SLC6A4
SCHEMBL31443748 0.81 DDB1 (0.45) CRBNDDB1HTR6SLC6A2SLC6A4
SCHEMBL31444154 0.79 DDB1 (0.45) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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