SCHEMBL31444132

SCHEMBL31444132

O=C(O)CN1CCC(c2ccc(N3CCC(=O)NC3=O)cc2OS(=O)(=O)F)CC1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 9/20 0.38
▸ CRBN Q96SW2 9/20 0.38
▸ IKZF2 Q9UKS7 2/20 0.35
▸ ADAM17 P78536 1/20 0.34
▸ ADAMTS5 Q9UNA0 1/20 0.34
▸ DRD4 P21917 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ SCN1A P35498 1/20 0.32
▸ SCN5A Q14524 1/20 0.32
▸ SCN9A Q15858 1/20 0.32
▸ CCNT1 O60563 2/20 0.32
▸ CDK9 P50750 2/20 0.32
▸ INSR P06213 1/20 0.32
▸ ALK Q9UM73 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443902 0.91 DDB1 (0.38) DDB1CRBNIKZF2ADAM17ADAMTS5
SCHEMBL31444154 0.88 DDB1 (0.45) DDB1CRBNADAM17ADAMTS5DRD4
SCHEMBL25169813 0.83 DDB1 (0.43) DDB1CRBNIKZF2DRD4KDM4E
SCHEMBL31444240 0.83 CRBN (0.43) DDB1CRBN
SCHEMBL31444046 0.83 CRBN (0.43) DDB1CRBN
SCHEMBL31443950 0.83 DDB1 (0.39) DDB1CRBNDRD4KDM4EALDH1A1
SCHEMBL31444055 0.81 DDB1 (0.44) DDB1CRBNKDM4EHPGDSCN9A
SCHEMBL31444014 0.81 CRBN (0.40) DDB1CRBNIKZF2
SCHEMBL31443969 0.80 DDB1 (0.45) DDB1CRBNDRD4CDK9
SCHEMBL31443705 0.79 CRBN (0.43) DDB1CRBNIKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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