SCHEMBL31444154

SCHEMBL31444154

CC(C)(C)OC(=O)CN1CCC(c2ccc(N3CCC(=O)NC3=O)cc2OS(=O)(=O)F)CC1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 11/20 0.45
▸ CRBN Q96SW2 11/20 0.45
▸ CNR1 P21554 1/20 0.36
▸ CDK9 P50750 1/20 0.35
▸ MDM2 Q00987 2/20 0.35
▸ WNT1 P04628 1/20 0.34
▸ GSK3B P49841 1/20 0.34
▸ DYRK1A Q13627 1/20 0.34
▸ ADAM17 P78536 1/20 0.32
▸ ADAMTS5 Q9UNA0 1/20 0.32
▸ CREBBP Q92793 1/20 0.32
▸ DRD4 P21917 1/20 0.32
▸ LMNA P02545 1/20 0.31
▸ TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443969 0.92 DDB1 (0.45) DDB1CRBNCNR1CDK9MDM2
SCHEMBL31444132 0.88 DDB1 (0.38) DDB1CRBNCDK9ADAM17ADAMTS5
SCHEMBL31444055 0.87 DDB1 (0.44) DDB1CRBN
SCHEMBL25447107 0.86 DDB1 (0.46) DDB1CRBNCNR1CDK9MDM2
SCHEMBL30313416 0.86 DDB1 (0.46) DDB1CRBNCNR1CDK9MDM2
SCHEMBL31443818 0.83 CRBN (0.47) DDB1CRBNMDM2
SCHEMBL31443815 0.81 CRBN (0.42) DDB1CRBNCNR1
SCHEMBL31443902 0.81 DDB1 (0.38) DDB1CRBNCDK9ADAM17ADAMTS5
SCHEMBL31323783 0.80 DDB1 (0.46) DDB1CRBNCNR1CDK9WNT1
SCHEMBL31443716 0.79 GPR119 (0.45) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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