SCHEMBL31444153

SCHEMBL31444153

COc1ccc(O)cc1OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.63
SMPD1 P17405 2/20 0.61
HDAC1 Q13547 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 1/20 0.55
HPGD P15428 1/20 0.55
RAB9A P51151 1/20 0.55
MAPK1 P28482 1/20 0.55
HSD17B10 Q99714 1/20 0.55
RXRA P19793 1/20 0.54
HTR1A P08908 1/20 0.54
ADRA1D P25100 1/20 0.54
ADRA1A P35348 1/20 0.54
ADRA1B P35368 1/20 0.54
MRGPRX4 Q96LA9 1/20 0.54
ELANE P08246 1/20 0.53
CTSG P08311 1/20 0.53
ATM Q13315 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6035592 1.00 BCHE (0.63) BCHESMPD1HDAC1HDAC8HDAC6
SCHEMBL6881536 0.93 BCHE (0.63) BCHESMN1; SMN2NPC1HPGDRAB9A
SCHEMBL8728948 0.89 SLC2A1 (0.59) BCHEHDAC6SMN1; SMN2NPC1HPGD
SCHEMBL29721165 0.89 SLC2A1 (0.59) BCHEHDAC6SMN1; SMN2NPC1HPGD
SCHEMBL10796837 0.85 KDM4E (0.60) HDAC6SMN1; SMN2NPC1HPGDRAB9A
SCHEMBL7736572 0.84 ABCB1 (0.59) SMN1; SMN2HTR1AADRA1DADRA1AADRA1B
SCHEMBL3239903 0.83 BCHE (0.60) BCHESMPD1HDAC1HDAC8HDAC6
SCHEMBL31361425 0.83 BCHE (0.60) BCHESMPD1HDAC1HDAC8HDAC6
SCHEMBL13791570 0.83 MAOB (0.62) BCHESMPD1HDAC1HDAC8HDAC6
SCHEMBL2090976 0.83 MAOB (0.62) BCHESMPD1HDAC1HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed