Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.63 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | CTSG | P08311 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444153 | 1.00 | BCHE (0.63) | BCHESMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL6881536 | 0.93 | BCHE (0.63) | BCHESMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL8728948 | 0.89 | SLC2A1 (0.59) | BCHEHDAC6SMN1; SMN2NPC1HPGD | |
| SCHEMBL29721165 | 0.89 | SLC2A1 (0.59) | BCHEHDAC6SMN1; SMN2NPC1HPGD | |
| SCHEMBL10796837 | 0.85 | KDM4E (0.60) | HDAC6SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL7736572 | 0.84 | ABCB1 (0.59) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3239903 | 0.83 | BCHE (0.60) | BCHESMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL31361425 | 0.83 | BCHE (0.60) | BCHESMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL13791570 | 0.83 | MAOB (0.62) | BCHESMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL2090976 | 0.83 | MAOB (0.62) | BCHESMPD1HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096856-A1 | COVALENT CEREBLON LIGANDS | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-106220487-B | A kind of chalcones derivative, preparation method, pharmaceutical composition and application | 上海市奉贤区中心医院 | 2018-10-02 | — | — | CN | disclosed |
| CN-106220487-A | A kind of chalcones derivant, preparation method, pharmaceutical composition and application | 上海市奉贤区中心医院 | 2016-12-14 | — | — | CN | disclosed |
| US-20070173548-A1 | Malonamic acids and derivatives thereof as thyroid receptor ligands | CHIANG YUAN-CHING P | 2007-07-26 | — | — | US | disclosed |
| US-20070173548-A1 | Malonamic acids and derivatives thereof as thyroid receptor ligands | CHIANG YUAN-CHING P | 2007-07-26 | — | — | US | disclosed |
| US-7202275-B2 | Malonamic acids and derivatives thereof as thyroid receptor ligands | WARNER LAMBERT COMPANY LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202275-B2 | Malonamic acids and derivatives thereof as thyroid receptor ligands | WARNER LAMBERT COMPANY LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| US-4633006-A | ARTIFICIAL SWEETENERS | GENERAL FOODS CORPORATION (US) | 1986-12-30 | — | — | US | disclosed |
| US-4626442-A | 3-hydroxy-4-alkyloxyphenyl heterocyclic aromatic carboxylates | GENERAL FOODS CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |
| US-4602095-A | 3-hydroxy-4-alkyloxyphenyl heterocyclic aromatic carboxylates | GENERAL FOODS CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| US-4579748-A | Foodstuff containing 3-hydroxy-4-methoxyphenyl benzoates | GENERAL FOODS CORP. (US) | 1986-04-01 | — | — | US | disclosed |
| US-4547584-A | 3-Hydroxy-4-methoxyphenyl benzoates | GENERAL FOODS CORPORATION (US) | 1985-10-15 | — | — | US | disclosed |
| US-4546000-A | 3-Hydroxy-4-alkyloxyphenyl aliphatic carbonates | GENERAL FOODS CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| US-4545999-A | 3-Hydroxy-4-methoxyphenyl aryl carbonates | GENERAL FOODS CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| US-4544566-A | 3-Hydroxy-4-alkyloxyphenyl heterocyclic carbonates | GENERAL FOODS CORPORATION (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0151293-A2 | 3-hydroxy-4-methoxyphenyl benzoates, process for modifying the sweetness perception in a foodstuff and foodstuff compositions containing said sweetening agents | GENERAL FOODS CORPORATION (US) | 1985-08-14 | — | — | EP | disclosed |
| EP-0146913-A2 | 3-hydroxy-4-alkyloxyphenyl heterocyclic aromatic carboxylates, foodstuffs containing said compounds as sweetening agents and process for modifying the sweetness perception in a foodstuff | GENERAL FOODS CORPORATION (US) | 1985-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | BCHE 1107/4885SMPD1 2000/4885HDAC1 398/4885 |
| US-20070173548-A1 | Malonamic acids and derivatives thereof as thyroid receptor ligands | THRA, MC1R, TSHR | BCHE 1300/4885SMPD1 3118/4885HDAC1 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.