SCHEMBL8728948

SCHEMBL8728948

Oc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.59
LMNA P02545 3/20 0.57
CYP1A2 P05177 1/20 0.57
PTGS1 P23219 1/20 0.57
SLC6A2 P23975 1/20 0.57
CYP2C19 P33261 1/20 0.57
PTGS2 P35354 1/20 0.57
SLC6A3 Q01959 1/20 0.57
HIF1A Q16665 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
KMT2A Q03164 2/20 0.51
C5AR1 P21730 1/20 0.51
POLB P06746 1/20 0.51
UBE2N P61088 1/20 0.51
ELANE P08246 3/20 0.50
BCHE P06276 2/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
F2 P00734 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29721165 1.00 SLC2A1 (0.59) SLC2A1LMNACYP1A2PTGS1SLC6A2
SCHEMBL11320083 0.91 SLC2A1 (0.56) SLC2A1LMNACYP1A2PTGS1SLC6A2
SCHEMBL10796837 0.91 KDM4E (0.60) SLC2A1LMNACYP1A2PTGS1SLC6A2
SCHEMBL30791321 0.90 SLC2A1 (0.58) SLC2A1LMNACYP1A2PTGS1SLC6A2
SCHEMBL21633635 0.90 SLC2A1 (0.58) SLC2A1LMNACYP1A2PTGS1SLC6A2
SCHEMBL6881536 0.89 BCHE (0.63) CYP1A2KMT2ABCHEKDM4EHPGD
SCHEMBL31444153 0.89 BCHE (0.63) LMNAHDAC6KMT2AELANEBCHE
SCHEMBL6035592 0.89 BCHE (0.63) LMNAHDAC6KMT2AELANEBCHE
SCHEMBL21633577 0.88 C5AR1 (0.58) SLC2A1LMNACYP1A2PTGS1SLC6A2
SCHEMBL10801528 0.88 C5AR1 (0.52) SLC2A1LMNACYP1A2PTGS1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828163-B1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME AUTOTAC INC (KR) 2026-05-20 EP disclosed
EP-3828164-B1 NOVEL AUTOPHAGY-TARGETING CHIMERA (AUTOTAC) COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING DISEASES THROUGH TARGET PROTEIN DEGRADATION COMPRISING SAME AUTOTAC INC (KR) 2025-10-29 EP disclosed
US-12427346-B2 P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same AUTOTAC INC. (KR) 2025-09-30 US disclosed
US-12383624-B2 Cargo delivery system and composition comprising the same SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-12 US disclosed
EP-3828162-B1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING PROTEINOPATHIES COMPRISING THE SAME AUTOTAC INC (KR) 2025-07-09 EP disclosed
US-12129218-B2 AUTOTAC chimeric compound, and composition for preventing, ameliorating or treating diseases through targeted protein degradation comprising the same AUTOTAC INC. (KR) 2024-10-29 US disclosed
EP-4373813-A1 COMPOUNDS AND METHODS FOR DETECTION OF SUPEROXIDE PROMEGA CORPORATION (US) 2024-05-29 EP disclosed
US-11981618-B2 P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same AUTOTAC INC. (KR) 2024-05-14 US disclosed
CN-112672993-B Novel AUTOTAC chimeric compounds and compositions comprising same for preventing, ameliorating or treating diseases by targeted protein degradation 奧土择破利悟株式会社 2024-03-08 CN disclosed
US-11802114-B2 Compounds and methods for detection of superoxide PROMEGA CORPORATION (US) 2023-10-31 US disclosed
US-5726165-A HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS SMITHKLINE BEECHAM P.L.C. (GB) 1998-03-10 US disclosed
EP-0778267-A1 SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-06-11 EP disclosed
EP-0772585-A1 ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF SMITHKLINE BEECHAM PLC (GB) 1997-05-14 EP disclosed
WO-1996004234-A1 ARYLOXY ANDARYCTHIO PROPANOLAMINE DERIVATIVES USEFUL AS B3-ADRENORECEPTOR AGONISTS AND ANTAGONS OF THE B1 AND B2 ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF SMITHKLINE BEECHAM PLC (GB) 1996-02-15 WO disclosed
WO-1996004233-A1 ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF SMITHKLINE BEECHAM PLC (GB) 1996-02-15 WO disclosed
EP-0346367-A1 ARYL- AND ARYLOXY-SUBSTITUTED TERT.-ALKYLENAMINES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE IN PHARMACY SCHERING AKTIENGESELLSCHAFT (DE) 1989-12-20 EP disclosed
WO-1988006580-A1 ARYL- AND ARYLOXY-SUBSTITUTED TERT.-ALKYLENAMINES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE IN PHARMACY SCHERING AKTIENGESELLSCHAFT (DE) 1988-09-07 WO disclosed
US-4695585-A 7-oxabicyclo(2.2.1)heptane analogs useful as inhibitors of 5-lipoxygenase and cyclooxygenase E. R. SQUIBB & SONS, INC. (US) 1987-09-22 US disclosed
US-4013777-A BRONCHODILATORS SMITHKLINE CORPORATION (US) 1977-03-22 US disclosed
US-3933837-A 3,4-Methylenedioxyphenoxy-alkyl diketones and keto-esters STERLING DRUG INC. (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12427346-B2 P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same SQSTM1, ATG7, BECN1 SLC2A1 1584/4885LMNA 364/4885CYP1A2 4604/4885
US-12129218-B2 AUTOTAC chimeric compound, and composition for preventing, ameliorating or treating diseases through targeted protein degradation comprising the same ATG7, SQSTM1, CTSA SLC2A1 522/4885LMNA 601/4885CYP1A2 4395/4885
US-12383624-B2 Cargo delivery system and composition comprising the same ATG7, SQSTM1, BECN1 SLC2A1 397/4885LMNA 1430/4885CYP1A2 4798/4885
US-11802114-B2 Compounds and methods for detection of superoxide SOD1, GPX4, SOD3 SLC2A1 1703/4885LMNA 1365/4885CYP1A2 334/4885
US-11981618-B2 P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same SQSTM1, ATG7, BECN1 SLC2A1 1774/4885LMNA 250/4885CYP1A2 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.