SCHEMBL31444231

SCHEMBL31444231

O=C(O)c1cnc(N2CCCCCC2c2ccccc2Cl)cc1F

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.41
FFAR2 O15552 7/20 0.40
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
NTRK1 P04629 7/20 0.38
TACR1 P25103 2/20 0.37
TACR3 P29371 2/20 0.37
CNR2 P34972 1/20 0.37
JAK2 O60674 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444405 0.96 HSP90AA1 (0.43) SCN9AFFAR2HSP90AA1HSP90AB1NTRK1
SCHEMBL31444410 0.96 HSP90AA1 (0.43) SCN9AFFAR2HSP90AA1HSP90AB1NTRK1
SCHEMBL31444386 0.88 SCN9A (0.42) SCN9AFFAR2HSP90AA1HSP90AB1NTRK1
SCHEMBL31443502 0.79 SCN9A (0.44) SCN9ANTRK1JAK2
SCHEMBL31444371 0.78 NTRK1 (0.38) FFAR2HSP90AA1HSP90AB1NTRK1
SCHEMBL31444375 0.76 HSP90AA1 (0.42) FFAR2HSP90AA1HSP90AB1NTRK1
SCHEMBL31444295 0.76 PDE5A (0.46) FFAR2HSP90AA1HSP90AB1
SCHEMBL31444378 0.75 RIPK1 (0.41) FFAR2HSP90AA1HSP90AB1NTRK1
SCHEMBL24313136 0.73 PRCP (0.41)
SCHEMBL31444272 0.71 HSP90AA1 (0.43) FFAR2HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072451-A1 RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES VIVIDION THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed