Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313474 | 0.84 | PRCP (0.43) | PRCPMAPTCYP17A1 | |
| SCHEMBL29849049 | 0.81 | CRHBP (0.48) | KDM4EMAPTL3MBTL1CHRNA7 | |
| SCHEMBL21491331 | 0.81 | CRHBP (0.48) | KDM4EMAPTL3MBTL1CHRNA7 | |
| SCHEMBL21491330 | 0.81 | CRHBP (0.48) | KDM4EMAPTL3MBTL1CHRNA7 | |
| SCHEMBL29456542 | 0.81 | CRHBP (0.48) | KDM4EMAPTL3MBTL1CHRNA7 | |
| SCHEMBL21491441 | 0.81 | CRHBP (0.48) | KDM4EMAPTL3MBTL1CHRNA7 | |
| SCHEMBL24313222 | 0.80 | JAK2 (0.35) | PRCPKDM4EMAPTL3MBTL1CYP17A1 | |
| SCHEMBL24654694 | 0.78 | PRCP (0.35) | PRCPCYP17A1 | |
| SCHEMBL24654724 | 0.78 | PSEN1 (0.39) | PRCPKDM4EMAPTL3MBTL1CHRNA7 | |
| SCHEMBL24313221 | 0.77 | HDAC6 (0.43) | PRCPKDM4EMAPTL3MBTL1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784666-B1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |