Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.52 |
| ▸ | CA2 | P00918 | 10/20 | 0.52 |
| ▸ | CA9 | Q16790 | 10/20 | 0.52 |
| ▸ | CA12 | O43570 | 8/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | CDK1 | P06493 | 4/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | CDK9 | P50750 | 3/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.49 |
| ▸ | CCNH | P51946 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 4/20 | 0.49 |
| ▸ | CA6 | P23280 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567494 | 0.90 | CDK1 (0.58) | CA1CA2CA9CA12CA14 | |
| SCHEMBL5561870 | 0.78 | CDK2 (0.64) | AURKAAURKBCDK1CCNT1CCNB1 | |
| SCHEMBL31180414 | 0.76 | PTK2 (0.56) | AURKACDK1CCNT1CCNB1CDK2 | |
| SCHEMBL31180415 | 0.76 | PTK2 (0.56) | AURKACDK1CCNT1CCNB1CDK2 | |
| SCHEMBL24477790 | 0.75 | CDK1 (0.60) | CA1CA2CA9CA12CA14 | |
| SCHEMBL29631744 | 0.75 | CDK1 (0.60) | CA1CA2CA9CA12CA14 | |
| SCHEMBL24477765 | 0.75 | CDK2 (0.60) | CA1CA2CA9AURKAAURKB | |
| SCHEMBL31444285 | 0.73 | LRRK2 (0.50) | CA1CA2CA9AURKAAURKB | |
| SCHEMBL29631616 | 0.73 | PTK2 (0.49) | AURKACDK1CCNT1CCNB1CDK2 | |
| SCHEMBL4062140 | 0.72 | CA2 (0.66) | CA2AURKAAURKBCDK1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532473-A1 | AMINOHETEROARYL KINASE INHIBITORS | Allorion Therapeutics Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119343333-A | Amino heteroaryl kinase inhibitors | 安锐生物医药公司 | 2025-01-21 | — | — | CN | disclosed |