SCHEMBL31444253

SCHEMBL31444253

Fc1cccc(C2CC3(CC3)CN2)c1F

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
TP53 P04637 2/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444476 0.84 OPRL1 (0.34) CHRNB2CHRNA4
SCHEMBL2328899 0.73 RAD52 (0.38) HTR2CHTR2BSLC6A2SLC6A4SLC6A3
SCHEMBL24774588 0.73 ADAM10 (0.33) HTR2CCHRNB2CHRNA4
SCHEMBL3396699 0.68 PRCP (0.40)
SCHEMBL31444531 0.68 MEN1 (0.43) HTR2CHTR2BCHRNB2CHRNA4
SCHEMBL22455759 0.68 MEN1 (0.43) HTR2CHTR2BCHRNB2CHRNA4
SCHEMBL31738967 0.68 MEN1 (0.43) HTR2CHTR2BCHRNB2CHRNA4
SCHEMBL29588230 0.68 MEN1 (0.43) HTR2CHTR2BCHRNB2CHRNA4
SCHEMBL31444475 0.67 MEN1 (0.42) HTR2CHTR2BTP53SLC6A2SLC6A4
SCHEMBL18588947 0.67 HTR2C (0.41) HTR2CHTR2BSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072451-A1 RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES VIVIDION THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed