SCHEMBL31444335

SCHEMBL31444335

COC(=O)C1OCC(=O)N(Cc2ccc(OC)cc2)C1c1cccc(F)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 2/20 0.41
SLC5A2 P31639 2/20 0.41
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HCRTR1 O43613 5/20 0.37
HCRTR2 O43614 5/20 0.37
CHRM1 P11229 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
BACE1 P56817 1/20 0.37
CYP3A4 P08684 1/20 0.36
RORC P51449 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444354 0.92 MEN1 (0.39) SLC5A1SLC5A2ALDH1A1HCRTR1HCRTR2
SCHEMBL31444317 0.85 SLC5A2 (0.40) SLC5A1SLC5A2ALDH1A1HCRTR1HCRTR2
SCHEMBL31444485 0.83 RORC (0.39) SLC5A1SLC5A2ALDH1A1HCRTR1HCRTR2
SCHEMBL18151450 0.81 MEN1 (0.48) ALDH1A1MEN1KMT2ABACE1
SCHEMBL31444487 0.77 HCRTR2 (0.56) SLC5A1SLC5A2HCRTR1HCRTR2MEN1
SCHEMBL14920390 0.73 KMT2A (0.45) ALDH1A1HCRTR1HCRTR2MEN1KMT2A
SCHEMBL18150950 0.73 KMT2A (0.50) ALDH1A1MEN1KMT2A
SCHEMBL20424244 0.69 TDP1 (0.50) ALDH1A1SMN1; SMN2MEN1KMT2ABACE1
SCHEMBL15989605 0.69 MDM2 (0.51) ALDH1A1HCRTR1HCRTR2MEN1KMT2A
SCHEMBL15989606 0.69 MDM2 (0.51) ALDH1A1HCRTR1HCRTR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072451-A1 RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES VIVIDION THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed