Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19745457 | 1.00 | GAA (0.56) | GAASMN1; SMN2TP53RECQLALDH1A1 | |
| SCHEMBL14458002 | 0.79 | SRD5A1 (0.52) | GAASMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL31444260 | 0.79 | SMN1; SMN2 (0.44) | GAASMN1; SMN2TP53RECQLALDH1A1 | |
| SCHEMBL9025372 | 0.79 | SMN1; SMN2 (0.50) | GAASMN1; SMN2TP53RECQLALDH1A1 | |
| SCHEMBL24282772 | 0.79 | TNKS2 (0.42) | GAAALDH1A1TNKS2IKBKBRAB9A | |
| SCHEMBL16796822 | 0.79 | DDB1 (0.57) | GAAALDH1A1KDM4EHSD17B10TNKS2 | |
| SCHEMBL22201148 | 0.79 | DDB1 (0.57) | GAAALDH1A1KDM4EHSD17B10TNKS2 | |
| SCHEMBL5889291 | 0.79 | IKBKB (0.42) | GAASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL1438939 | 0.77 | SMN1; SMN2 (0.45) | GAASMN1; SMN2TP53RECQLALDH1A1 | |
| SCHEMBL1438936 | 0.77 | SMN1; SMN2 (0.45) | GAASMN1; SMN2TP53RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |