Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16796822 | 1.00 | DDB1 (0.57) | DDB1CRBNHTR2CPBRM1TNKS2 | |
| SCHEMBL16796979 | 0.79 | ALDH1A1 (0.43) | DDB1CRBNPBRM1ALDH1A1KDM4E | |
| SCHEMBL29748101 | 0.79 | DDB1 (0.43) | DDB1CRBNHTR2CPBRM1TNKS2 | |
| SCHEMBL29747631 | 0.79 | DDB1 (0.43) | DDB1CRBNHTR2CPBRM1TNKS2 | |
| SCHEMBL7870683 | 0.79 | DDB1 (0.47) | DDB1CRBNHTR2CPBRM1TNKS2 | |
| SCHEMBL24282772 | 0.79 | TNKS2 (0.42) | DDB1CRBNTNKS2ALDH1A1IKBKB | |
| SCHEMBL19745457 | 0.79 | GAA (0.56) | DDB1CRBNPBRM1TNKS2ALDH1A1 | |
| SCHEMBL5889291 | 0.79 | IKBKB (0.42) | DDB1CRBNALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31444352 | 0.79 | GAA (0.56) | DDB1CRBNPBRM1TNKS2ALDH1A1 | |
| SCHEMBL16796768 | 0.78 | CRBN (0.39) | DDB1CRBNHTR2CIKBKBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |