Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16344586 | 0.88 | MEN1 (0.42) | IKBKBDDB1CRBNRAB9AGAA | |
| SCHEMBL620338 | 0.83 | AR (0.42) | RAB9AGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL22201148 | 0.79 | DDB1 (0.57) | IKBKBDDB1CRBNRAB9AGAA | |
| SCHEMBL31444352 | 0.79 | GAA (0.56) | IKBKBDDB1CRBNRAB9AGAA | |
| SCHEMBL19745457 | 0.79 | GAA (0.56) | IKBKBDDB1CRBNRAB9AGAA | |
| SCHEMBL24282772 | 0.79 | TNKS2 (0.42) | IKBKBDDB1CRBNRAB9AGAA | |
| SCHEMBL16796822 | 0.79 | DDB1 (0.57) | IKBKBDDB1CRBNRAB9AGAA | |
| SCHEMBL16096236 | 0.78 | IKBKB (0.40) | IKBKBDDB1CRBNRAB9AGAA | |
| SCHEMBL25742792 | 0.77 | PIN1 (0.38) | IKBKBDDB1CRBNMEN1KMT2A | |
| SCHEMBL16796841 | 0.75 | HTR2C (0.49) | IKBKBDDB1CRBNGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122506-B2 | Cyclic imines as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2006-10-17 | — | — | US | disclosed |
| CN-1198800-C | 2- (2-chlorophenyl) -3, 4-dihydro-2H-pyrrole derivatives | BAYER AG (DE) | 2005-04-27 | — | — | CN | disclosed |
| EP-1077938-B1 | 2-(2-METHYLPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2005-04-13 | — | — | EP | disclosed |
| US-20040186287-A1 | Cyclic imines as pesticides | PLANT ANDREW (DE) | 2004-09-23 | — | — | US | disclosed |
| EP-1080072-B1 | 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2004-08-04 | — | — | EP | disclosed |
| US-6770595-B2 | ACTIVITY AGAINST ARTHROPODS IN AGRICULTURE AND PARASITES ENCOUNTERED IN ANIMAL HUSBANDRY | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-03 | — | — | US | disclosed |
| US-6599924-B1 | 2-hetaryl-3,4 dihydro-2H-pyrrole pesticide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |
| EP-1306371-A1 | Cyclic imines | Bayer CropScience AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| EP-0942901-B1 | CYCLIC IMINES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-03-05 | — | — | EP | disclosed |
| US-6489490-B1 | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-03 | — | — | US | disclosed |
| US-20020151571-A1 | Cyclic imines as pesticides | PLANT ANDREW (DE) | 2002-10-17 | — | — | US | disclosed |
| US-6399771-B1 | AGRICULTURE; VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-04 | — | — | US | disclosed |
| CN-1309636-A | 2-(2-chlorophenyl)-3,4-dihydro-2H-pyrrol derivs. | BAYER AG (DE) | 2001-08-22 | — | — | CN | disclosed |
| US-6274613-B1 | APPLYING COMPOUNDS SUCH AS A GAMMA-ETHOXY-GAMMA-BUTYROLACTAM TO PESTS AND/OR THEIR HABITATS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-14 | — | — | US | disclosed |
| EP-1121357-A1 | 2-HETARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-08-08 | — | — | EP | disclosed |
| EP-1080072-A1 | 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-03-07 | — | — | EP | disclosed |
| WO-2000021958-A1 | 2-HETARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999059968-A1 | 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| EP-0942901-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022438-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151571-A1 | Cyclic imines as pesticides | DDT, CYP1A1, AR | IKBKB 4031/4885DDB1 788/4885CRBN 711/4885 |
| US-20040186287-A1 | Cyclic imines as pesticides | DDT, CYP1A1, AR | IKBKB 4095/4885DDB1 789/4885CRBN 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.