Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444552 | 0.81 | HDAC6 (0.41) | HSP90AA1HSP90AB1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL31444483 | 0.80 | ALOX15 (0.42) | HSP90AA1HSP90AB1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL31444344 | 0.76 | KMT2A (0.44) | ALOX15HSD17B10MAPTKMT2A | |
| SCHEMBL31444296 | 0.72 | TP53 (0.38) | HSP90AA1HSP90AB1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL30989311 | 0.72 | MRGPRX4 (0.49) | HSP90AA1HSP90AB1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL29285091 | 0.72 | MRGPRX4 (0.49) | HSP90AA1HSP90AB1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL12765031 | 0.70 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL31444386 | 0.69 | SCN9A (0.42) | HSP90AA1HSP90AB1ALDH1A1HPGDKDM4E | |
| SCHEMBL16880723 | 0.68 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1HSD17B10ALDH1A1HPGD | |
| SCHEMBL31444406 | 0.67 | HDAC6 (0.44) | ALDH1A1MAPTRBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |