Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444319 | 0.87 | HPGD (0.39) | TP53HSP90AA1HPGDALDH1A1GAA | |
| SCHEMBL31443660 | 0.78 | SCN9A (0.34) | HCRTR2 | |
| SCHEMBL31443759 | 0.74 | SCN9A (0.36) | HCRTR2 | |
| SCHEMBL31443501 | 0.74 | SCN9A (0.36) | HCRTR2 | |
| SCHEMBL20976884 | 0.73 | MAPT (0.51) | TP53HPGDALDH1A1TSHRGAA | |
| SCHEMBL31444401 | 0.73 | NR1H4 (0.39) | HSP90AA1HSP90AB1NR1H4DRD2DRD1 | |
| SCHEMBL31444483 | 0.72 | ALOX15 (0.42) | HSP90AA1HSP90AB1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL31444429 | 0.72 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1DRD2DRD1DRD4 | |
| SCHEMBL16608992 | 0.72 | RAB9A (0.53) | TP53ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL31444409 | 0.71 | NR1H4 (0.41) | HSP90AA1HSP90AB1NR1H4DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |