Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10217092 | 1.00 | CTSS (0.41) | CTSSCTSKATMKMT2AALDH1A1 | |
| SCHEMBL257267 | 0.90 | AVPR2 (0.45) | ATMKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL10216878 | 0.88 | CTSS (0.42) | CTSSCTSKATMKMT2AALDH1A1 | |
| SCHEMBL31444515 | 0.88 | CTSS (0.42) | CTSSCTSKATMKMT2AALDH1A1 | |
| SCHEMBL13306842 | 0.88 | CTSS (0.42) | CTSSCTSKATMKMT2AALDH1A1 | |
| SCHEMBL10217126 | 0.86 | PPARG (0.44) | CTSSCTSKATMKMT2AALDH1A1 | |
| SCHEMBL1147244 | 0.85 | CTSA (0.56) | CTSA | |
| SCHEMBL10217095 | 0.85 | ATM (0.43) | CTSSCTSKATMKMT2ALMNA | |
| SCHEMBL5768896 | 0.84 | RAB9A (0.45) | ATMKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL22805380 | 0.84 | CTSS (0.44) | CTSSCTSKATMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |