Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31419219 | 0.85 | ROCK2 (0.47) | RIPK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL23064594 | 0.85 | RIPK1 (0.43) | RIPK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL31444298 | 0.83 | ROCK2 (0.38) | PDE5ATSHRNR1H2STSALDH1A1 | |
| SCHEMBL30078453 | 0.83 | CYP1A2 (0.42) | RIPK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL38659898 | 0.82 | RIPK1 (0.64) | RIPK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL4035098 | 0.82 | RIPK1 (0.64) | RIPK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL4035101 | 0.82 | RIPK1 (0.64) | RIPK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL28234024 | 0.82 | RIPK1 (0.64) | RIPK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL27139334 | 0.80 | RIPK1 (0.44) | RIPK1PDE5AGRM5HSP90AA1HSP90AB1 | |
| SCHEMBL31444419 | 0.80 | TSHR (0.55) | RIPK1TSHRSTSALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |